About Myasthenia Gravis

Microscope and lab equipment used for Myasthenia Gravis research

What is Myasthenia Gravis? 

Myasthenia Gravis, sometimes called MG, is a rare, autoimmune, neuromuscular condition that causes muscle weakness and fatigue.(1) In fact, the name literally means “serious muscle weakness,” which is the main symptom.(2)

The disease can affect any voluntary muscle, including those controlling eye movements, facial expression, speaking and swallowing, and arms and legs. In more life-threatening cases, MG can affect muscles responsible for breathing.(3-4)

The most common symptoms of the disease (3-4)

Eyelid drooping

Blurred or double vision

Difficulty speaking

Difficulty chewing/swallowing

Difficulty supporting neck

Shortness of breath/difficulty breathing

Difficulty walking/standing

Weakness in the arms and legs

Chocking

Fatigue from repeated muscle use

Did you know ?


Between 56,000 and 100,000 people are affected by MG in Europe (5).

There are 6 types of MG: generalised MG, ocular MG, seronegative MG, congenital MG, juvenile MG and transient neonatal MG. (1,6,7)

MG is not genetic (inherited), and it’s not contagious. (2,8,9)

MG can affect people of any age, but it is more common in women under 40 and men over 60. (10)

Explore more useful content

Doctor explaining why Myasthenia Gravis happens to a patient

Why does MG happen?

 

Have you ever heard of the neuromuscular junction? It's at the centre of the conversation when we try to understand why MG happens.

Healthcare professional reviewing six types of Myasthenia Gravis on tablet

The 6 types of MG

 

MG comes in many types with differing symptoms. Let’s discover and learn more about the 6 types of MG.​

Benefits of MG tracking

Consistency with tracking is essential to better understand symptoms, their impact and how they can change over time

Patient's consultation with doctor

Initiate the conversation with your doctor

Living with myasthenia gravis shouldn't stop you from doing the things you love. By talking to your healthcare professional, you can find a management plan that is tailored to your personal goals.

REFERENCES :

1. Hehir MK, et al. Neurol Clin. 2018;36(2):253-260.

2. Myasthenia Gravis Fact Sheet. National Institute of Neurological Disorders and Stroke Website. Updated March 2020. Accessed May 2020. https://www.ninds.nih.gov/myasthenia-gravis-fact-sheet

3. Grob D, et al. Muscle Nerve. 2008;37(2):141-149.

4. Myasthenia Gravis. Muscular Dystrophy Association Website. Accessed November 2022. https://www.mda.org/disease/myasthenia-gravis/signs-and-symptoms

5. Le fardeau de la myasthénie auto-immune en Belgique. Livre blanc. 2022; Juin. 

6. Farrugia ME, et al. Front Neural. 2020;11:604.

7. O'Connell K, et al. Front Neurol. 2020;11:743.

8. Ramanujam R, et al. Twin Res Hum Genet. 2011;14:129-136.

9. Szobor A. Acta Med Hung. 1989;46(1):13-21.

10. Mantegazza R, et al. Ann N Y Acad Sci. 2003;998:413-23.

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